It depends on tghe type of sound that you're looking, Jabocaster. If you want a sound with high output, and sharp tone, the choice is Gibson 500 T, and you can dig to the rest of the guitar players of your area, sure. Explorers and Flyings have this pick ups, are brutal.
If you want a distorted warm sound, with great mids and lows, the choice is a Di Marzio DP 155 (Tone Zone), is a very warm pick up, but gives lower output than 500 T. Other option is DP 100 (Super distortion model) these cream pick ups used in these classic albums..have a very warm and strong tone. Not use PAF PRO!! Ibanez Jem models uses this humbuckers,,and have poor sound, compared with guitars like Jackson Soloist, different Kramer (Baretta, Focus) Robin (specially Medley series), Gibsons or ESP (Mirage custom), for example.
If you wants a classic rock distortion, you can try with Seymour Duncan JB, (TB4), have a great tone, very good balanced pick up. If you want put a EMG 81, for example in a Strato-type guitar, the batteries matter is a bad thing, you should remove the pickguard in every change, i don't like this. And i don't like the tone, sounds like Hi-Fi, but some guitar players with great sound uses them, Like Zakk Wylde, or Kerry King, using Marshall 800 Amplification (the best choice for metal).