Hi azhockeynut ...
First of all, your guitars are great.
You can get a good tone IMHO with your setup, i don´t know crate powerblock, because i never play whith one of these, but,can you set a marshall simulation in this gear ??? I´m a user of behringer vamp2, pod 2.0, pod xt live, and now i have line6 toneport whith line6 gear box software, i allways use a marshall jcm or marshall plexi simulation and thats good for me. I dont´ set a lot of gain, generally i set gain (or drive knob ok) with 65%, and add reverb or cut delay. I also use an real overdrive pedal too, then i combine drive from pedal with drive from software, but in this case i set gain in software with 30% or less, and add´s drive/gain with a real pedal. Sounds good too.
Is very rare i use compressor, or other modulation effects, for me a lot of effects doesn´t sounds good, and adds a lot of digital character in tone, then i prefer set only a drive with some delay or reverb (less drive sounds better for me then a lot of drive).
If you interest, check my youtube channel, i up many vid´s with line6 gear box (with overdrive pedal too in some vid´s).